What is it?
Dupuytren’s disease is an abnormal thickening of the fascia (the tissue just beneath the skin of
the palm). It often starts with firm lumps in the palm. In some patients, firm cords will develop
beneath the skin, stretching from the palm into the fingers (see Figure 1). Gradually, these
cords may cause the fingers to bend into the palm (see Figure 2). Although the skin may
become involved in the process, the deeper structures—such as the tendons—are not directly
involved.
Occasionally, the disease will cause thickening on top of the finger knuckles (knuckle
pads), or nodules or cords within the soles of the feet (plantar fibromatosis).
What causes it?
The cause of Dupuytren’s disease is unknown but may be associated with certain biochemical
factors within the involved fascia. The problem ismore common in men over age 40 and in
people of northern European descent. There is no proven evidence that hand injuries or specific
occupational exposures lead to a higher risk of developing Dupuytren’s disease.
What are the symptoms and signs?
Symptoms of Dupuytren’s disease usually include a small lump or series
of lumps and pits within
the palm. The lumps are generally firm and adherent to the skin. Gradually a cord may develop,
extending from
the palm into one or more fingers, with the ring and little fingers most commonly
affected. These cords may be mistaken for tendons, but they actually lie between the skin and the
tendons. In many cases, both
hands are affected, although the degree of involvement may vary.
The initial nodules may produce discomfort that usually resolves, but Dupuytren’s disease is not
typically painful. The disease may first be noticed because of difficulty placing the hand flat on
an even surface,
such as a tabletop (see Figure 3). As the fingers are drawn into the palm,
one may notice increasing difficulty with activities such as washing, wearing gloves, shaking
hands, and putting hands into pockets. Progression is unpredictable. Some individuals will have
only small lumps or cords while others will develop severely bent fingers. More severe disease often occurs with an earlier age of onset.
What are the treatment options?
In some cases, only observation is needed for nodules and cords that are
not contracted.
Patients with more advanced contractures may require surgery in order to improve function.
Various surgical techniques are available in order to correct finger position. Your treating
surgeon will discuss the method most appropriate for your condition based upon the stage
of the disease and the joints involved (see Figure 4). The goal of surgery is to improve finger
position and thereby hand function. Despite surgery, the disease process may recur and the
fingers may begin to bend into the palm once again. Before
surgery, your treating surgeon
will discuss realistic goals and results.
Specific surgical considerations:
1. The presence of a lump in the palm does not mean that surgery is sss
required or that the disease will progress.
2. Correction of finger position is best accomplished with milder contractures and
contractures that affect the base of the finger. Complete correction sometimes can not
be attained, especially of the middle and end joints in the finger.
3. Skin grafts are sometimes required to cover open areas in the fingers if the skin is
deficient.
4. The nerves that provide feeling to the fingertips are often intertwined with the cords.
5. Splinting and hand therapy are often required after surgery in order to maximize and
maintain the improvement in finger position and function.